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. 2011 Jan 21;60(2):517–524. doi: 10.2337/db10-0266

FIG. 3.

FIG. 3.

TXNIP is present in human adipose tissue and adipocytes and is regulated by glucose. A: TXNIP gene and protein expression levels during adipocyte differentiation of human primary adipocytes or human SGBS adipocytes. B: Western blot images of caspase-1 and TXNIP protein levels in total human subcutaneous adipose tissue (n = 2). C: Relative gene expression levels of TXNIP in mature adipocytes or the SVF isolated from human adipose tissue (n = 3). D: Gene expression levels of TXNIP in intact adipose tissue treated with various concentrations of glucose (n = 3). E: Gene expression levels of TXNIP in human primary adipocytes treated with various concentrations of glucose (n = 3). F: Protein levels of TXNIP in human adipose tissue after 5 mM glucose, 25 mM glucose, or 5 mM deoxyglucose treatment for 48 h (n = 2). G: Protein levels of TXNIP after glucose starvation (no glucose), 5 mM glucose, and 25 mM glucose for 48 h in human primary adipocytes. *P < 0.05; **P < 0.01 using a one-way ANOVA test (D and E) or a Student t test (C).