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. 2011 Jan 21;60(2):590–601. doi: 10.2337/db10-0403

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© 2011 by the American Diabetes Association.

Readers may use this article as long as the work is properly cited, the use is educational and not for profit, and the work is not altered. See http://creativecommons.org/licenses/by-nc-nd/3.0/ for details.

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FIG. 5. — Smad7 gene therapy attenuates diabetic kidney injury in rats. A: Blood glucose. B: Microalbuminuria. C: Histology. When compared with the diabetic rats (DM) and empty vector control DM rats (VC), Smad7 gene therapy attenuates microalbuminuria and ECM deposition within the glomerulus and tubulointerstitium. Data represent mean ± SE for groups of six animals. **P < 0.01 vs. normal; ###P < 0.001 vs. DM and VC. (A high-quality color representation of this figure is available in the online issue.)