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. 2011 Jan 21;60(2):644–651. doi: 10.2337/db10-0346

TABLE 2.

Effect of teglicar treatment on different parameters of db/db mice after long-term treatment (45 days unless otherwise specified)

Control Teglicar
Body weight (g) 40.0 ± 1.1 40.4 ± 2.2
Food intake (g/day) 6.71 ± 0.2 5.46 ± 0.4
Water intake (mL/day) 13.5 ± 0.2 9.38 ± 1.1*
Serum parameters
 Glycemia (day 28) (mg/dL) 495 ± 28 250 ± 20*
 Glycemia (day 35) (mg/dL) 570 ± 30 322 ± 25*
 Glycemia (mg/dL) 576 ± 32 352 ± 25*
 Fructosamine (mmol/L) 4.8 ± 0.1 3.36 ± 0.3*
 Insulin (ng/mL) 2.81 ± 0.2 2.32 ± 0.3
 Triglycerides (mg/dL) 80.7 ± 5.5 82.2 ± 6.1
 FFA (μmol/L) 1.98 ± 0.15 2.29 ± 0.1*
 Cholesterol (mg/dL) 110.4 ± 10.1 112.4 ± 6.1
 ALT (U/L) 82.9 ± 4.9 102.6 ± 7.2
Liver parameters
 Liver weight (g) 1.94 ± 0.08 1.93 ± 0.09
 Liver triglyceride content (mg/100 mg wt) 5.71 ± 0.9 8.54 ± 0.7*
 Liver glycogen (μmol/g wt) 329 ± 54 255 ± 46

Data are means ± SE of eight mice.

*P < 0.05 vs. controls.