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. Author manuscript; available in PMC: 2011 Jan 27.
Published in final edited form as: Cancer Epidemiol Biomarkers Prev. 2008 Sep;17(9):2393–2401. doi: 10.1158/1055-9965.EPI-08-0326

Table 3.

Stratified analysis for CYP1A1 I462V and Msp1 by gender, gene mutated, and ethnicity.

HR (95% CI) P HR (95% CI) P

Male Female
CYP1A1 I462V
AA Ref Ref
AG 1.65 (0.88 - 3.10) 0.12 1.99 (1.12 - 3.53) 0.019
AG+GG 1.65 (0.88 - 3.10) 1.61 (0.91 - 2.86) 0.09
CYP1A1 Msp1
TT Ref Ref
TC 1.34 (0.75 - 2.4) 0.33 1.58 (0.99 - 2.5) 0.052
TC+CC 1.34 (0.74 - 2.41) 0.33 1.39 (0.87 – 2.24) 0.17

MLH1 MSH2
CYP1A1 I462V
AA Ref Ref
AG 1.3 (0.82 - 2.03) 0.24 2.24 (1.22 - 4.12) 0.009
AG+GG 1.15 ( 0.79 - 1.81) 0.52 2.06 (1.14 - 3.72) 0.017
CYP1A1 Msp1
TT Ref Ref
TC 1.3 (0.82 - 2.07) 0.27 1.74 (1.12 - 2.69) 0.013
TC+CC 1.19 (0.74 - 1.91) 0.46 1.62 (1.04 - 2.54) 0.034

White Other
CYP1A1 I462V
AA Ref Ref
AG 1.73 (1.09 - 2.77) 0.021 2.19 (0.82 - 5.88) 0.12
AG+GG 1.53 (0.97 - 2.43) 0.066 2.11 (0.8 - 5.63) 0.13
CYP1A1 Msp1
TT Ref Ref
TC 1.5 (0.99 - 2.26) 0.052 1.04 (0.52 - 2.08) 0.91
TC+CC 1.41 (0.93 - 2.12) 0.1 0.93 (0.44 - 1.96) 0.85