Table 2.
Maximum severity, per patient, of grade 3 or 4 adverse events, n= 49
| Toxicity | Grade 3/Grade 4 | Total |
|---|---|---|
| Hematologic | ||
| Anaemia | 12% | 91% |
| Thrombocytopaenia | 20% | 67% |
| Neutropaenia | 37% | 59% |
| Lymphopaenia | 18% | 59% |
| Non-haematological | ||
| Fatigue | 6% | 61% |
| Transaminitis (AST/ALT) and increase in alkaline phosphatase | 4% | 41% |
| Nausea | 6% | 37% |
| Vomiting | 6% | 28% |
| Infection without neutropaenia | 4% | 13% |
| Hyperbilirubinaemia | 2% | 10% |
| Diarrhoea | 4% | 8% |
| Febrile neutropaenia with infection | 6% | 6% |
| Febrile neutropaenia without infection | 2% | 2% |
AST, aspartate aminotransferase; ALT, alanine aminotransferase.