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. 2010 Aug;12(6):427–433. doi: 10.1111/j.1477-2574.2010.00198.x

Table 3.

The majority of neuroendocrine tumours metastatic to the liver are from gastrointestinal primaries

Primary location n %
Small bowel 65 37.8%
Pancreas 55 32.0%
Appendix/cecum 8 4.7%
Colon 13 7.6%
Liver 6 3.5%
Lung/thymus 6 3.5%
Rectum 2 1.2%
Thyroid 4 2.3%
Ovary/mesentery 5 2.9%
Unknown 8 4.7%

All were biopsy-proven primaries with the exception of unknown primaries where hepatic lesions were biopsied prior to treatment and the pattern was consistent with neuroendcrine metastatic disease. Hepatic NET lesions found subsequent to primary hepatic NET resection were classified as metastatic hepatic NET. Pancreatic primaries include functional, non-functional, islet cell and non-islet cell NET.