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. 2010 Dec 13;31(4):845–860. doi: 10.1128/MCB.00159-10

FIG. 7.

FIG. 7.

Hbo1−/− embryos feature a general decrease in gene expression at E8.5 and E9.5, along with a reduction of H3K14 acetylation in gene coding regions. (A to D) RT-qPCR analysis of mRNA expression of patterning genes (A and B), vascular genes (C), and HAT genes (D) in stage-matched Hbo1+/+ and Hbo1−/− embryos at E8.5 (A) and E9.5 (B to D). (E and F) ChIP-qPCR analysis of H3K14 acetylation levels in the coding regions of Hoxa3, Tbx1, and Otx2 in stage-matched Hbo1+/+ and Hbo1−/− embryos at E8.5 (E) and normalized to H3K14 acetylation levels at Hsp90ab1 (F).