TABLE 4.
Significantly regulated functional categories for each of the five strains (compared to strain LD61) according to a Wilcoxon testa
Functional category or subcategory | Expression level in strain: |
||||
---|---|---|---|---|---|
UCMA5713 | LD55 | LL08 | LL52 | S86 | |
Amino acid biosynthesis | L | L | L | L | L |
Aromatic amino acid family | L | L | L | ||
Aspartate family | L | L | L | ||
Branched-chain family | L | L | L | L | L |
Histidine family | L | L | L | L | L |
Cellular processes | L | ||||
Chaperones | H | ||||
Transformation | H | ||||
Protein and peptide secretion | L | ||||
Biosynthesis of cofactors, prosthetic groups, and carriers | |||||
Menaquinone and ubiquinone | H | H | |||
Thioredoxin, glutaredoxin, and glutathione | L | ||||
Fatty acid and phospholipid metabolism | H | H | |||
Central intermediary metabolism | L | ||||
Other | L | L | L | L | |
Energy metabolism | L | ||||
Anaerobic | L | L | L | ||
ATP-PMF conversion | L | L | L | ||
Fermentation | L | ||||
Sugars | H | H | H | H | |
TCA cycleb | H | ||||
Other categories | L | ||||
Adaptations and atypical conditions | H | ||||
Transposon related functions | H | ||||
Purines, pyrimidines, nucleosides and nucleotides | L | L | L | L | L |
Purine ribonucleotide biosynthesis | L | L | L | L | |
Pyrimidine ribonucleotide biosynthesis | L | L | L | L | L |
Salvage of nucleosides and nucleotides | L | ||||
Sugar-nucleotide biosynthesis and interconversions | H | H | |||
Regulatory functions | L | L | L | L | |
AraC family regulators | L | ||||
General | L | ||||
LysR family regulators | L | L | |||
MarR family regulators | L | L | |||
Two-component systems | L | ||||
Replication | |||||
Degradation of DNA | H | H | H | H | |
Translation | L | ||||
Translation factors | L | ||||
Ribosomal proteins: synthesis and modification | H | ||||
Amino acyl tRNA synthetases | L | ||||
Transport and binding proteins | L | L | L | L | |
Amino acids, peptides and amines | L | L | |||
Anions | L | ||||
Carbohydrates, organic alcohols and acids | H |
P < 0.05. “H” and “L” indicate expression levels that are higher and lower, respectively, than those in LD61.
Tricarboxylic acid cycle.