TABLE 2.
In vitro susceptibilities of study strains to host defense CAPS differing in source, structure, and mechanism
| Strain | % survival (mean ± SD)a after 2-h exposure to indicated concn (μg/ml) of: |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| tPMP |
RP-1 |
hNP-1 |
PMB |
DAP |
||||||
| 0.25 | 0.125 | 5 | 2.5 | 20 | 10 | 80 | 40 | 1.25 | 0.625 | |
| SA144 | 4 ± 4 | 7 ± 1 | 11 ± 1 | 23 ± 9 | 20 ± 7* | 60 ± 2 | 13 ± 11 | 29 ± 4 | 12 ± 6 | 18 ± 14 |
| SA145 | 0 ± 0 | 2 ± 2 | 13 ± 2 | 18 ± 4 | 27 ± 13 | 60 ± 2 | 14 ± 7 | 23 ± 9 | 21 ± 15 | 24 ± 9 |
| SA147 | 8 ± 2 | 14 ± 1 | 23 ± 9 | 55 ± 12 | 52 ± 13** | 66 ± 2 | 26 ± 13 | 25 ± 6 | 49 ± 15 | 55 ± 7 |
a
*, P = 0.0037 (SA144 versus SA147); **, P = 0.087 (SA145 versus SA 147).