TABLE 3.
Susceptibilities (MIC50 and MIC90) of bacterial enteropathogens isolated from subjects with travelers' diarrhea studied in Mexico, Guatemala, and India, 2006 to 2008
| Antibiotic |
C. jejuni (n = 23)a |
ETEC (n = 365) |
EAEC (n = 23) |
Plesiomonas spp. (n = 10) |
Salmonella spp. (n = 15) |
Shigella spp. (n = 13) |
Aeromonas spp. (n = 4) |
||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MIC50 (μg/ml) | MIC90 (μg/ml) | Range (μg/ml) | MIC50 (μg/ml) | MIC90 (μg/ml) | Range (μg/ml) | MIC50 (μg/ml) | MIC90 (μg/ml) | Range (μg/ml) | MIC50 (μg/ml) | MIC90 (μg/ml) | Range (μg/ml) | MIC50 (μg/ml) | MIC90 (μg/ml) | Range (μg/ml) | MIC50 (μg/ml) | MIC90 (μg/ml) | Range (μg/ml) | MIC50 (μg/ml) | MIC90 (μg/ml) | Range (μg/ml) | |
| AMP | 4 | 4 | 1-4 (0)b | 64 | >1,024 | 1->1,024 (52) | 16 | >1,024 | 2->1,024 (52) | 1 | 2 | 0.5-2 (0) | 2 | 2 | 1-2 (0) | 8 | 128 | 2-128 (38) | 4 | 4 | 4 (0) |
| NAL | 8 | 16 | 0.015-16 (0) | 8 | >1,024 | 0.015->1,024 (47) | 32 | >1,024 | 1->1,024 (56) | 0.5 | 1 | 0.25-1 (0) | 4 | 4 | 4 (0) | 4 | 64 | 1-64 (47) | 0.125 | 0.25 | 0.125-0.25 (0) |
| TET | 2 | 2 | 0.25-4 (0) | 128 | 256 | 0.015->1,024 (58) | 2 | 256 | 0.5-256 (48) | 0.25 | 0.25 | 0.25 (0) | 128 | 128 | 128 (100) | 128 | 128 | 64-128 (100) | 0.25 | 0.25 | 0.25 (0) |
| DOX | 2 | 4 | 0.015-4 (0) | 16 | 128 | 0.015-512 (51) | 64 | 256 | 1-512 (52) | 0.015 | 0.06 | 0.015-64 (10) | 128 | 128 | 128 (100) | 64 | 64 | 64-128 (100) | 0.015 | 0.015 | 0.015 (0) |
| T/S | 1 | 1 | 0.5-2 (0) | 4 | 128 | 0.015->1,024 (49) | >1,024 | >1,024 | 0.5->1,024 (59) | 0.5 | 0.5 | 0.5 (0) | 0.5 | 0.5 | 0.5-1 (0) | 64 | 64 | 64 (100) | 0.5 | 0.5 | 0.5 (0) |
| CFO | 0.03 | 0.06 | 0.03-0.125 (0) | 0.06 | 0.25 | 0.015-512 (5) | 0.06 | 64 | 0.015-1,024 (18) | 0.015 | 0.015 | 0.015 (0) | 0.06 | 0.06 | 0.06 (0) | 0.015 | 0.06 | 0.015-0.125 (0) | 0.015 | 0.015 | 0.015 (0) |
| RIF | 16 | 32 | 0.015-32 (22) | 8 | 32 | 0.25-32 (17) | 8 | 16 | 4-16 (0) | 8 | 8 | 8 (0) | 8 | 8 | 8-16 (0) | 16 | 16 | 8-16 (0) | 8 | 8 | 8 (0) |
| CIP | 0.015 | 0.03 | 0.015-0.03 (0) | 0.06 | 128 | 0.015->1,024 (20) | 0.03 | 512 | 0.015-512 (30) | 0.015 | 0.015 | 0.015 (0) | 0.015 | 0.015 | 0.015 (0) | 0.125 | 0.125 | 0.015-0.125 (0) | 0.015 | 0.015 | 0.015 (0) |
| LEV | 0.06 | 0.125 | 0.015-0.125 (0) | 0.125 | 8 | 0.015-128 (24) | 0.25 | 128 | 0.015-128 (39) | 0.015 | 0.015 | 0.015-0.125 (0) | 0.03 | 0.03 | 0.03 (0) | 0.03 | 0.25 | 0.015-0.25 (0) | 0.015 | 0.015 | 0.015 (0) |
| AZM | 0.5 | 1 | 0.03-2 (0) | 2 | 32 | 0.03-512 (18) | 1 | 64 | 0.25-64 (33) | 0.015 | 0.015 | 0.015-0.125 (0) | 1 | 1 | 1 (0) | 1 | 2 | 1-2 (0) | 0.015 | 0.015 | 0.015 (0) |
a
n, total number of isolates studied.
b
The numbers in parentheses represent the percentages of isolates with MICs indicating resistance based on the CLSI breakpoints.