TABLE 4.
Antibiotic | BPa | India |
Mexico and Guatemala |
||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Campylobacter (n = 17)b |
ETEC (n = 98) |
EAEC (n = 3) |
Campylobacter (n = 6) |
ETEC (n = 270) |
EAEC (n = 20) |
||||||||
MIC90 (μg/ml) | % Rc | MIC90 (μg/ml) | % R | MIC90 (μg/ml) | % R | MIC90 (μg/ml) | % R | MIC90 (μg/ml) | % R | MIC90 (μg/ml) | % R | ||
AMP | ≥32 | 4 | 0 | >1,024 | 49.4 | 4 | 0 | 4 | 0 | >1,024 | 52.8 | >1,024 | 60 |
NAL | ≥32 | 16 | 0 | >1,024 | 71.1 | 128 | 66.7 | 16 | 0 | >1,024 | 38.5 | >1,024 | 55 |
TET | ≥16 | 2 | 0 | 256 | 52.5 | 1 | 0 | 2 | 0 | 256 | 59.2 | 256 | 55 |
DOX | ≥16 | 4 | 0 | 128 | 48.5 | 4 | 0 | 2 | 0 | 64 | 51.9 | 256 | 60 |
T/S | ≥8/152 | 1 | 0 | 64 | 58.9 | 1 | 0 | 2 | 0 | 128 | 46 | >1,024 | 65 |
CFO | ≥32 | 0.06 | 0 | 0.5 | 6.2 | 0.06 | 0 | 0.06 | 0 | 0.25 | 4.8 | 64 | 20 |
RIF | ≥32 | 32 | 29.4 | 32 | 19.6 | 8 | 0 | 16 | 0 | 32 | 15.5 | 16 | 0 |
CIP | ≥4 | 0.03 | 0 | 256 | 27.8 | 0.25 | 0 | 0.03 | 0 | 64 | 17.5 | 512 | 35 |
LEV | ≥8 | 0.125 | 0 | 8 | 40.8 | 0.5 | 0 | 0.06 | 0 | 8 | 20.1 | 128 | 45 |
AZM | ≥8d | 2 | 0 | 32 | 24.5 | 2 | 0 | 1 | 0 | 32 | 16.1 | 64 | 40 |
BP, CLSI breakpoint (resistant strains are at or above the BP, and susceptible strains are below the breakpoint).
n, total number of isolates studied.
% R, percent resistant, i.e., the MIC was above the CLSI breakpoint.
Based on established values for nonenteric bacterial pathogens.