TABLE 3.
LDR-FMA evaluation of pfmdr1 SNPs in laboratory-adapted Plasmodium falciparum strainsb
| Strain | MFI for pfmdr1 codona: |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| 86 |
184 |
1034 |
1042 |
1246 |
||||||
| Y | N | Y | F | S | C | D | N | D | Y | |
| 3D7 | 2,657 | 15,306 | 17,956 | 6,464 | 21,903 | 5,568 | 225 | 21,182 | 5,243 | 327 |
| 7G8 | 1,724 | 11,351 | 1,869 | 21,092 | 1,475 | 16,556 | 6,022 | 436 | 746 | 1,421 |
| Dd2 | 12,684 | 3,418 | 15,465 | 5,891 | 22,008 | 5,061 | 234 | 18,333 | 4,357 | 359 |
| HB3 | 555 | 6,381 | 530 | 10,036 | 17,881 | 1,555 | 8,238 | 271 | 2,686 | 168 |
| K1 | 19,971 | 3,482 | 17,393 | 6,055 | 21,501 | 4,519 | 199 | 18,265 | 3,476 | 543 |
a
pfmdr1 haplotypes for P. falciparum strains are NYSND for 3D7, NFCDY for 7G8, YYSND for Dd2, and NFSDD for HB3.
b
The fluorescence signal is expressed as median fluorescence intensity (MFI) units. Boldface type indicates positive allele-specific signals.