TABLE 4.
Fluorescence intensity detection thresholds and maxima for Plasmodium falciparum pfdhps, pfdhfr, pfcrt, and pfmdr1 in field samples
| Gene and allelea | Fluorescence intensity signal |
|
|---|---|---|
| Threshold | Maximum | |
| pfdhps | ||
| 540K | 1,213 | 20,400 |
| 540E | 9,774 | |
| 581A | 1,940 | 21,876 |
| 581S* | ||
| 613A | 2,374 | 21,403 |
| 613S* | ||
| pfdhfr | ||
| 51I* | 4,147 | |
| 51N | 23,429 | |
| 59R | 6,087 | 23,368 |
| 59C | 23,490 | |
| 108T* | 3,348 | |
| 108S | 16,258 | |
| 108N | 22,198 | |
| 164I | 3,914 | 19,695 |
| 164L* | ||
| pfcrt | ||
| CVIET* | 4,791 | |
| CVMNK | 20,657 | |
| SVMNT | 22,523 | |
| pfmdr1 | ||
| 86Y | 6,722 | 21,994 |
| 86N | 18,189 | |
| 184Y | 7,899 | 21,145 |
| 184F | 20,412 | |
| 1034S | 11,166 | 25,792 |
| 1034C* | ||
| 1042D | 2,836 | 10,973 |
| 1042N | 23,200 | |
| 1246D | 1,410 | 9,921 |
| 1246Y | 3,174 | |
a
Alleles not detected in the field isolates are indicated with an asterisk.