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Concentration-dependent in vitro release of E. multilocularis PGI activities after metacestode damage induced by mefloquine. Metacestodes were incubated for 5 days with different concentrations (1 to 100 μM) of mefloquine. Levels of concentration-dependent parasite damage were assessed by the PGI assay and are depicted as percentages of total metacestode damage (obtained by addition of Triton X-100 to achieve a 1% concentration).
