TABLE 2.
Microarray analysis shows that exposure to monensin causes significant upregulation in transcription of Toxoplasma genesa
| GeneID | Function/homology | Fold upregulation |
|---|---|---|
| TGME49 039260 | Histone H4 | 23.1 |
| TGME49 105160 | Histone H2Ba | 11.6 |
| TGME49 045880 | Hypothetical protein | 8.8 |
| TGME49 068970 | Hypothetical protein | 8.3 |
| TGME49 000400 | Protein phosphatase 2A | 8.2 |
| TGME49 065320 | Cell cycle control protein encoded by cwf2 | 7.2 |
| TGME49 061240 | Histone H3 | 7.0 |
| TGME49 018740 | Hypothetical protein | 6.8 |
| TGME49 014410 | Hypothetical protein | 6.5 |
| TGME49 100050 | Hypothetical protein | 6.3 |
| TGME49 077230 | Hypothetical protein | 6.1 |
| TGME49 061580 | Histone H2AX | 5.9 |
| TGME49 061390 | Hypothetical protein | 5.1 |
| TGME49 070260 | Hypothetical protein | 5.0 |
| TGME49 092980 | Hypothetical protein | 4.9 |
| TGME49 045770 | Hypothetical protein | 4.8 |
| TGME49 026540 | Protein kinase | 4.8 |
| TGME49 106510 | Hypothetical protein | 4.8 |
| TGME49 108820 | Hypothetical protein | 4.7 |
| TGME49 089920 | Hypothetical protein | 4.7 |
| TGME49 061250 | Histone H2A | 4.5 |
| TGME49 017610 | Hypothetical protein | 4.3 |
| TGME49 023560 | Hypothetical protein | 4.1 |
| TGME49 008370 | Myosin heavy chain | 4.0 |
| TGME49 106620 | Platelet binding protein GspB (AP2 domain containing) | 4.0 |
| TGME49 115570 | Histone H1 | 3.9 |
| TGME49 038440 | SRS22A | 3.9 |
| TGME49 050120 | Hypothetical protein | 3.8 |
| TGME49 119360 | SRS17 | 3.8 |
| TGME49 105930 | Hypothetical protein | 3.8 |
a
Shown are the 30 genes with the largest transcriptional upregulation in response to monensin exposure (2.5 ng/ml for 24 h).