TABLE 3.
Changes in transcript abundance of all known putative Toxoplasma histone subunits in response to monensina
| GeneID | Putative histone subunit | Fold change |
|---|---|---|
| TGME49 115570 | H1 | 3.9 up |
| TGME49 061250 | H2A | 4.5 up |
| TGME49 105160 | H2B | 11.6 up |
| TGME49 061240 | H3 | 7.0 up |
| TGME49 039260 | H4 | 23.1 up |
| TGME49 061580 | H2AX | 5.9 up |
| TGME49 100200 | H2AZ | 2.3 down |
| TGME49 009910 | H2Bv1 | NSC |
| TGME49 018260 | H3.3 | NSC |
| TGME49 025410 | CenH3 | 1.8 down |
a
All of the transcripts were validated by qPCR. NSC, no significant change in transcript abundance. Canonical histone subunits are shown in bold. See text for discussion of methods of microarray analysis and statistical comparison. up, upregulation; down, downregulation.