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VAN-allograft does not inhibit adherence of the Gram-negative E. coli. VAN affects Gram-positive but not Gram-negative bacteria. A control allograft or VAN-allograft was challenged with the Gram-negative organism E. coli DH5α (Ci = 104 CFU/ml), for 2, 5, 8, or 12 h. After extensive rinsing, numbers of adherent bacteria were determined by colony counting. It is noteworthy that there was no statistical difference in numbers of organisms adherent to the surfaces at each time interval.
