TABLE 2.
Routine laboratory results for patients
Patient | Laboratory resulta |
|||||||||
---|---|---|---|---|---|---|---|---|---|---|
Creatinine (mg/dl) | Urea (mg/dl) | Bilirubin (mg/dl) | AST (U/liter) | ALT (U/liter) | GGT (U/liter) | PT (%) | WBC (109 cells/liter) | Hb (g/liter) | PLT (109 cells/liter) | |
Baseline testing | ||||||||||
1 | 0.40 | 46.6 | 6.12 | 55 | 40 | 1,317 | 86 | 27.0 | 95 | 185 |
2 | 0.88 | 69.7 | 11.00 | 60 | 149 | 686 | 70 | 10.6 | 77 | 106 |
3 | 0.73 | 60.8 | 9.75 | 61 | 50 | 148 | 50 | 11.8 | 97 | 24 |
4 | 1.47 | 83.2 | 0.95 | 20 | 40 | 480 | 90 | 7.1 | 99 | 21 |
5 | 1.12 | 76.1 | 8.63 | 235 | 214 | 2,534 | 72 | 9.1 | 79 | 136 |
6 | 0.68 | 81.1 | 1.14 | 33 | 22 | 232 | 76 | 4.5 | 89 | 21 |
7 | 0.64 | 47.1 | 0.28 | 15 | 9 | 35 | 90 | 16.9 | 91 | 241 |
8 | 0.92 | 62.0 | 0.93 | 50 | 40 | 433 | 77 | 5.2 | 91 | 296 |
Median | 0.81 | 65.9 | 3.63 | 53 | 40 | 457 | 77 | 9.9 | 91 | 121* |
Interquartile range | 0.36 | 24.7 | 8.25 | 34 | 69 | 812 | 17 | 8.2 | 12 | 191 |
Final testing | ||||||||||
1 | 0.40 | 46.6 | 6.12 | 55 | 40 | 1,317 | 86 | 27.0 | 95 | 185 |
2 | 1.99 | 106.7 | 9.29 | 221 | 109 | 1,129 | 67 | 13.5 | 84 | 15 |
3 | 0.62 | 80.5 | 15.33 | 107 | 75 | 180 | 51 | 9.5 | 101 | 12 |
4 | 0.98 | 57.1 | 3.45 | 43 | 66 | 338 | 89 | 7.0 | 74 | 18 |
5 | 0.89 | 60.5 | 7.93 | 205 | 186 | 1,827 | 70 | 6.2 | 87 | 112 |
6 | 1.53 | 183.1 | 0.46 | 31 | 20 | 209 | 108 | 3.1 | 73 | 28 |
7 | 3.07 | 250.7 | 0.36 | 1,079 | 667 | 102 | 25 | 39.9 | 108 | 108 |
8 | 2.45 | 100.5 | 1.00 | 56 | 29 | 656 | 82 | 6.6 | 88 | 177 |
Median | 1.26 | 90.5 | 4.79 | 82 | 71 | 497 | 76 | 8.25 | 88 | 82* |
Interquartile range | 1.47 | 86.1 | 7.88 | 164 | 113 | 1,029 | 29 | 13.9 | 19 | 128 |
The results from routine laboratory tests on the first day of VRC treatment (baseline testing) and final routine laboratory test results are shown as follows: serum creatinine, normal range, 0.51 to 1.17 mg/dl; urea, normal range 18 to 55 mg/dl; plasma bilirubin, normal range, 0.00 to 1.29 mg/dl; aspartate aminotransferase (AST), normal range, 10 to 50 U/liter; alanine aminotransferase (ALT), normal range, 10 to 50 U/liter; γ-glutamyl transferase (GGT), normal range, 6 to 71 U/liter; prothrombin time (PT), normal range 70 to 130%; white blood cell (WBC) count, normal range, 4.0 × 109 to 10.0 × 109 cells/liter; hemoglobin (Hb), normal range, 120 to 177 g/liter; and platelet (PTL) count, normal range, 150 × 109 to 380 × 109 cells/liter. *, significant differences between the first and last testings (Wilcoxon matched-pairs test). No significant increases in liver and renal function tests were observed during VRC therapy. Since all patients were on sedoanalgesia, neurotoxicity of VRC could not be assessed.