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Maximum specific artemisone uptake and rate of uptake into infected erythrocytes (parasitemia corrected) at a range of initial external concentrations of radiolabeled artemisone
| Concn (μM) | Mean uptake max (million molecules per cell) for parasite fraction ± SEM |
Mean rate constant (h−1) for parasite fraction ± SEM |
||
|---|---|---|---|---|
| Pellet | Supernatant | Pellet | Supernatant | |
| 0.4 | 2.7 ± 0.7 | 0.20 ± 0.06 | 17 ± 2 | 16 ± 3 |
| 4 | 30 ± 5 | 2.7 ± 0.3 | 2.3 ± 0.2 | 3.6 ± 0.7 |
| 20 | 110 ± 20 | 10 ± 2 | 1.1 ± 0.1 | 1.5 ± 0.3 |
