TABLE 2.

Substitutions unique to viruses displaying BMS-488043 resistance

Subject and sample	Substitution at:
	V68	L116	S375	M426
Virus with emerging loss of susceptibility to BMS-488043
1
Baseline	—a	—	—	—
Day 8	A	—	N	—
4
Baseline	—	—	—	—
Day 8	—	—	N	—
21
Baseline	—	—	—	—
Day 8	—	—	N	—
25
Baseline	—	—	—	—
Day 8	—	—	N	—
Virus with preexisting resistance to BMS-488043
10
Baseline	—	—	I	—
Day 8	—	—	I	—
19
Baseline	—	I	—	—
Day 8	—	I	—	—
27
Baseline	—	—	—	L
Day 8	—	—	—	L
30
Baseline	—	—	—	L
Day 8	—	—	—	L

^a—, no change from consensus sequence.