TABLE 3.
Effect of gp120 68V/375N on BMS-488043 sensitivitya
Background | Amino acid at position: |
EC50 (nM) | Fold change in sensitivity compared to baseline | |
---|---|---|---|---|
68 | 375 | |||
1-8-4 | A | N | 3,645 | 499 |
V | N | 386 | 53 | |
A | S | 56 | 8 | |
V | S | 4.8 | 0.7 | |
1-8-5 | V | N | 278 | 38 |
A | N | >10,000 | >1,370 | |
V | S | 21 | 3 |
In the context of the envelope gene from subject 1.