FIG. 4.

Immunization or infection on its own does not induce proinflammatory gene expression in the stomach. Gene expression was measured in mice immunized sublingually with H. pylori lysate together with CT before challenge with live H. pylori bacteria (Ly + CT b.c.) as well as in unimmunized infected mice (UI) at day 28 postchallenge and compared to the basal gene expression detected in naïve animals. The mean level of the different transcripts was set to 1 in the naïve group for each gene. Pooled data from two independent experiments are shown as mean values for groups of five to nine animals; error bars represent SEM. No significant differences were detected for any of the investigated genes.