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. 2010 Nov 29;79(2):695–707. doi: 10.1128/IAI.01071-10

FIG. 2.

FIG. 2.

Alteration in the mRNA concentrations of TNF-α, IL-1A, IL-6, and IFN-β (IFN-β1 and IFN-β2) in pbMEC after challenge with E. coli (⧫) and S. aureus (□) particles. Shown are values for mean fold induction (ordinate, ± standard error of the mean [SEM]; n = 3) at times after challenge (abscissa) relative to the mRNA concentration measured for unstimulated cells (set as 1). Asterisks indicate a statistical significance (*, P ≤ 0.05; **, P ≤ 0.01 [by t test]) of the difference between the E. coli and S. aureus values at the time indicated. The IL-1A insert shows a Western blot analysis of IL-1A in lysates (20 μg/slot) from unchallenged pbMEC (0 h) and from those challenged for 2 h or 4 h with S. aureus or E. coli particles (107 particles/ml). The band shows the 31-kDa IL-1A precursor protein.