TABLE 2.
CD8+ cell subset frequencies in HIV-infected and uninfected individuals
| Cell subset | % CD8+ cells among subjects who weree: |
|||
|---|---|---|---|---|
| HIV− (n = 19) | TxHIV+ (n = 12) | EC (n = 15) | vHIV+ (n = 31) | |
| CD38+ | 64 (50-69) | 62 (49-69) | 60 (55-70) | 70 (59-76) |
| HLA-DR+ | 15 (10-32) | 31 (22-46) | 33 (25-46) | 49d (36-62) |
| CD27+ | 22 (19-26) | 26 (20-31) | 21 (17-23) | 31d (25-37) |
| CD28+ | 57 (49-71) | 47 (38-53) | 40 (33-56) | 35a,c (27-46) |
| CD25+ | 4 (3-6) | 5 (3-6) | 3 (2-4) | 2a,c (1-4) |
| CD122+ | 31 (19-44) | 16 (11-25) | 21 (18-29) | 17a (13-26) |
| CD45RO+ | 35 (28-46) | 50 (43-54) | 42 (34-48) | 47a (38-58) |
| CD45RA+ | 69 (59-83) | 67 (57-72) | 73 (64-78) | 59a,b (52-71) |
| CD57+ | 19 (12-22) | 43 (30-54) | 36 (32-41) | 41a (34-55) |
| CD62L+ | 62 (54-71) | 50 (45-57) | 52 (43-58) | 42d (36-49) |
| CD11b+ | 31 (19-41) | 15 (7-27) | 17 (11-21) | 10a,b (6-16) |
| PD-1+ | 9 (6-15) | ND | 18 (15-23) | 44a,b (34-51) |
a
Significantly different from the value for HIV− subjects (P < 0.05).
b
Significantly different from the value for EC subjects (P < 0.05).
c
Significantly different from the value for TxHIV+ subjects (P < 0.05).
d
Signficantly different from the values for HIV−, EC, and TxHIV+ subjects (P < 0.05).
e
Values are medians (interquartile ranges). ND, no data.