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Histopathology in large airway and parenchyma. Ferrets were inoculated i.n. with 106 PFU of each virus, and tissues were collected on day 3 p.i. for analysis. Inflammation and epithelial necrosis is seen in the large airways (A to C) and interstitial and intraalveolar inflammation in the parenchyma (D to F) of ferrets inoculated with Mx/4482 virus (representative of 2009 H1N1 viruses) (A, D), OH/2 virus (B, E), or TX/14 virus (C, F).
