FIG. 3.
Inoculation location does not affect WNV viremia in mice. Mice were needle inoculated in two locations: s.c. with 105 PFU of WNV-BHK in the left rear footpad and i.v. with diluent alone (solid line, filled symbols) or 200 PFU of WNV (dashed line, open symbols) into the tail vein (n = 15 or 16 mice per group per time point). Serial serum samples were harvested at various times postinoculation, and plaque assays were performed. Error bars represent standard errors of the means. The horizontal dashed line indicates an LOD of 50 PFU/ml.