FIG. 7.

Teriparatide-induced bone bridging is required for improved biomechanical properties of the scaffold-grafted femurs. The scaffold-grafted femurs were tested in torsion to determine their biomechanical properties, including maximum torque (A, B), torsional rigidity (C, D), and ultimate normalized rotation or twist (E, F). (B, D, F) The maximum torque, torsional rigidity, and ultimate twist, respectively, of specimens that developed a bridging union compared to nonunion control and teriparatide-treated specimens. Data are presented as mean ± standard error of the mean. Asterisk indicates significant differences from control (p < 0.05).