Table 1.
Baseline demographic, hematological, clinical, and virological information of the study population
| Dengue (N = 154) | OFI (N = 200) | P value* | |
|---|---|---|---|
| Demographics | |||
| Male gender (%) | 89 (57.8) | 121 (60.5) | 0.700 |
| Age in years (SD) | 39.4 (13.4) | 36.6 (13.2) | 0.040 |
| Chinese ethnicity (%)† | 119 (77.3) | 133 (66.5) | 0.030 |
| Days from illness onset at enrollment (SD) | 2.1 (0.8) | 1.8 (0.8) | < 0.001 |
| Clinical presentation | |||
| Headache (%) | 126 (81.8) | 132 (66.0) | 0.001 |
| Retro-orbital pain (%) | 41 (26.6) | 27 (13.5) | 0.003 |
| Myalgia (%) | 106 (68.8) | 123 (61.5) | 0.200 |
| Arthralgia (%) | 96 (62.3) | 107 (53.5) | 0.100 |
| Rash (%) | 16 (10.4) | 6 (3.0) | 0.007 |
| Nausea (%) | 79 (51.3) | 61 (30.5) | < 0.001 |
| Vomiting (%) | 25 (16.2) | 17 (8.5) | 0.030 |
| Mucosal bleed (%) | 11 (7.1) | 6 (3.0) | 0.080 |
| Abdominal pain (%) | 12 (7.8) | 43 (21.5) | < 0.001 |
| Leukopenia < 4.5 × 103/μL (%) | 111 (72.1) | 23 (11.5) | < 0.001 |
| Thrombocytopenia < 100 × 103/μL (%) | 23 (14.9) | 3 (1.5) | < 0.001 |
| DENV serotype | |||
| DENV-1 (%) | 54 (35.1) | ||
| DENV-2 (%) | 46 (29.9) | ||
| DENV-3 (%) | 54 (35.1) | ||
| DENV-4 (%) | 0 | ||
| Serological status | |||
| Primary infection (%) | 75 (48.7) | ||
| Secondary infection (%) | 79 (51.3) | ||
*
Continuous variables, t test; categorical variables, Fisher's exact test.
†
Other ethnic groups in the study population were Malays, Indians, and Caucasians.