Table 1. Cell geometry and physical parameters.
Parameter | Definition | Value | Value [ref.] |
F | Faraday constant | 96478 C/mol | |
R | Ideal gas constant | 8314 mJ/(mol K) | |
T | Temperature | 306.15 K | |
[Na+]o | Extracellular Na+ concentration | 130 mM | |
[Ca2+]o | Extracellular Ca2+ concentration | 1.8 mM | |
[K+]o | Extracellular K+ concentration | 5.4 mM | |
Cm | Cell membrane capacitance | 0.05 nF | 0.0519±0.035 nF [10] |
0.041 nF [11] | |||
0.058±0.078 nF [16] | |||
rjunct | Radius of the bulk cytosol | 6.5 µm | 4.6±0.3 µm [74] |
7.8 µm [11] | |||
7.4±0.15 µm [70] | |||
lcell | Length of the cell | 122.051 µm | 88±6.1 µm [74] |
111.3±6.5 µm [75] | |||
101.1±1.5 µm [70] | |||
Vss | Volume of the subspace | 4.99232×10−5 nL | |
Δr | Width of bulk cytosol compartments | 1.625 µm | ∼2 µm [12], [13] |