Table 1. Cell geometry and physical parameters.

Parameter	Definition	Value	Value [ref.]
F	Faraday constant	96478 C/mol
R	Ideal gas constant	8314 mJ/(mol K)
T	Temperature	306.15 K
[Na+]o	Extracellular Na+ concentration	130 mM
[Ca2+]o	Extracellular Ca2+ concentration	1.8 mM
[K+]o	Extracellular K+ concentration	5.4 mM
Cm	Cell membrane capacitance	0.05 nF	0.0519±0.035 nF [10]
			0.041 nF [11]
			0.058±0.078 nF [16]
rjunct	Radius of the bulk cytosol	6.5 µm	4.6±0.3 µm [74]
			7.8 µm [11]
			7.4±0.15 µm [70]
lcell	Length of the cell	122.051 µm	88±6.1 µm [74]
			111.3±6.5 µm [75]
			101.1±1.5 µm [70]
Vss	Volume of the subspace	4.99232×10−5 nL
Δr	Width of bulk cytosol compartments	1.625 µm	∼2 µm [12], [13]