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. 2011 Jan 27;6(1):e15993. doi: 10.1371/journal.pone.0015993

Table 1. Results of simulations.

Population Type and Size 100 RILs 200 F2 1000 F2
Selection Intensity 10% 30% 10% 30% 10% 30%
Confidence Detection Thresholds
95% 1.18 0.7 0.58 0.34 0.27 0.15
99% 1.43 0.85 0.72 0.42 0.33 0.19
Model Effect Chromosome No. Position (cM) Failure Rate (%)
1 Major Additive Two 36 0.1 0 0 0 0 0
2 Major Dominant Two 36 0 0 0 0 0 0
3 Moderate Additive Two 36 12.5 4 10.4 3 0 0
4 Maj. Overdominance Two 36 94.5 95.9 95.2 95.4 95.1 94.7
5 Major Additive Two 2 0 0 0 0 0 0
6 Moderate Additive (unlinked) Two 36 20.1 10.4 14.7 5.5 0 0
6 Moderate Additive (unlinked) Five 41 17.4 7.7 12.2 4.4 0 0
7 Major Additive (linked in repulsion) Two 36 24.1 42.3 55.5 48.9 0.7 0.5
7 Major Additive (linked in repulsion) Two 56 29.8 45.1 58.5 52.6 0.9 0.2
8 Major Epistasis (unlinked) Two 36 31.5 17.9 55.4 63.4 3 11.9
8 Major Epistasis (unlinked) Five 41 32.6 15.7 58.7 65.3 3.9 12.3
Model Effect Chromosome No. Position (cM) 95% Confidence Interval (cM)
1 Major Additive Two 36 10.4 5.6 18.5 9.4 3.8 3.2
2 Major Dominant Two 36 11.2 5.4 20.5 14.4 4.3 3.6
3 Moderate Additive Two 36 55.2 32.9 63.6 45.3 9.2 5.8
4 Maj. Overdominance Two 36 83.0 83.0 83.0 83.0 83.0 83.0
5 Major Additive Two 2 6.2 3.1 10.8 6.4 2.0 0.4
6 Moderate Additive (unlinked) Two 36 60.1 52.4 66.1 61.0 10.2 6.7
6 Moderate Additive (unlinked) Five 41 71.7 43.8 73.5 57.1 9.2 6.4
7 Major Additive (linked in repulsion) Two 36 26.8 37.1 36.7 36.3 18.3 15.4
7 Major Additive (linked in repulsion) Two 56 30.1 29.4 28.8 28.5 22.7 16.1
8 Major Epistasis (unlinked) Two 36 77.2 58.2 83.0 83.0 42.6 71.3
8 Major Epistasis (unlinked) Five 41 98.0 76.2 98.0 98.0 46.4 79.8

(Top) The horizontal detection thresholds calculated by considering the minimum signal not exceeded by the unlinked chromosomes in 95 and 99% of the simulations.

(Middle) The rate of failure, as a percentage, for a linked chromosome to exceed the 95% threshold for detection constructed from the maximum and minimum values on unlinked chromosomes.

(Bottom) The 95% confidence intervals constructed representing the central width of the chromosome that contained the peak in 950 of 1000 simulations. These data represent the precision of the mapping technique for each model, population, and selection intensity.