Table 4. Contribution analysis of individual microRNAs in the overall best prediction model.
| microRNAs positively associated with recurrence | microRNAs negatively associated with recurrence | |||||||
| Rank | miR name | Tissue type | Coefficient | 95%CI† | miR name | Tissue type | Coefficient | 95%CI† |
| 1 | miR-96 § | N | 0.1349 | (0.1259∼0.1449) | miR-96 | T/N ratio | −0.0865 | (−0.0941∼−0.0793) |
| 2 | miR-139-5p | T/N ratio | 0.0750 | (0.0661∼0.0850) | miR-374b | T/N ratio | −0.0785 | (−0.0861∼−0.0710) |
| 3 | miR-139-5p | T | 0.0727 | (0.0646∼0.0815) | miR-182 | T/N ratio | −0.0604 | (−0.0659∼−0.0549) |
| 4 | miR-126* | T | 0.0676 | (0.0620∼0.0737) | miR-378 § | N | −0.0561 | (−0.0612∼−0.0511) |
| 5 | miR-142-3p | T | 0.0673 | (0.0599∼0.0749) | miR-193b | T/N ratio | −0.0543 | (−0.0600∼−0.0493) |
| 6 | miR-142-3p | T/N ratio | 0.0659 | (0.0575∼0.0754) | miR-193b | T | −0.0539 | (−0.0596∼−0.0483) |
| 7 | miR-362-3p | T | 0.0596 | (0.0538∼0.0659) | miR-214 | T/N ratio | −0.0535 | (−0.0585∼−0.0489) |
| 8 | miR-374b | N | 0.0563 | (0.0499∼0.0629) | miR-125b § | T | −0.0522 | (−0.0569∼−0.0479) |
| 9 | miR-10b | T | 0.0548 | (0.0482∼0.0616) | miR-125b | T/N ratio | −0.0521 | (−0.0565∼−0.0483) |
| 10 | miR-200a | N | 0.0544 | (0.0486∼0.0599) | miR-99b | T/N ratio | −0.0517 | (−0.0564∼−0.0474) |
| 11 | miR-224 | N | 0.0530 | (0.0466∼0.0599) | miR-1202 § | N | −0.0515 | (−0.0584∼−0.0451) |
| 12 | miR-483-3p | T | 0.0529 | (0.0459∼0.0602) | miR-18b | T/N ratio | −0.0513 | (−0.0590∼−0.0440) |
| 13 | miR-200a | T | 0.0527 | (0.0477∼0.0580) | miR-365 | T/N ratio | −0.0511 | (−0.0573∼−0.0454) |
| 14 | miR-1202 | T/N ratio | 0.0507 | (0.0441∼0.0574) | miR-100 | T/N ratio | −0.0506 | (−0.0559∼−0.0456) |
| 15 | miR-96 | T | 0.0484 | (0.0423∼0.0543) | miR-365 | T | −0.0504 | (−0.0563∼−0.0445) |
| 16 | miR-665 | T/N ratio | 0.0474 | (0.0413∼0.0534) | miR-210 | T | −0.0502 | (−0.0567∼−0.0440) |
| 17 | miR-1274a | T/N ratio | 0.0472 | (0.0428∼0.0518) | miR-100 § | T | −0.0500 | (−0.0547∼−0.0459) |
| 18 | miR-10b | T/N ratio | 0.0471 | (0.0408∼0.0533) | miR-214 | T | −0.0491 | (−0.0544∼−0.0443) |
| 19 | miR-665 | T | 0.0469 | (0.0411∼0.0528) | miR-378 § | T | −0.0489 | (−0.0536∼−0.0444) |
| 20 | miR-1228 | T/N ratio | 0.0446 | (0.0398∼0.0500) | miR-182 | T | −0.0476 | (−0.0534∼−0.0419) |
Positive and negative coefficients indicates that higher and reduced expression of microRNA is associated with recurrence, respectively.
§
: overlapped microRNAs in Table 2.
†
: CI, confidence interval, calculated by 1000 times bootstrap resampling.