Table 2. Individual analysis of auxological GHRS criteria.
Height <−3 SDS | Height <−1,5 SDS below the target height | Height <−2 SDS and height velocity <−1 SDS* | Height <−2 SDS and height diminution >0,5 SDS** | Normal height and height velocity <−2 SDS* | Normal height and height velocity <−1,5 SDS*** | At least one of the 6 criterion | |
Criterion completed at diagnosis n (%) (CI) | 11 (52%) (31–73) | 19 (90%) (77–100) | 21 (100%) (100–100) | 11 (52%) (31–73) | 5 (24%) (6–42) | 4 (19%) (2–36) | |
Age at criterion completion (yr) median (range) (IQR) | 1 (0,6; 10) (0.7; 2.2) | 1 (0; 9) (0.5; 1.8) | 2 (1; 9) (1; 3.9) | 3 (2; 6) (3; 4.3) | 3 (2; 6) (3; 4) | 3 (2; 4) (2.7; 3.2) | 1 (0; 4) (0.6; 2) |
Number of patients who completed the criterion first n (%) (CI) | 2 (18%) (0–41) | 16 (84%) (67–100) | 4 (19%) (2–36) | 0 (0%) (0–0) | 2 (40%) (3–83) | 1 (25%) (0–67) | |
Potential reduction of diagnostic delay among the patients who completed the criterion (yr) median (range) (IQR) | 2 (0; 6.8) (0.1; 3.3) | 2.1 (0; 12.6) (1.5; 2.9) | 1.5 (0; 9.6) (0; 3) | 0 (0; 1.5) (0; 0.3) | 2 (0.6; 4.5) (0.7; 2.1) | 2.7 (0.5; 6.5) (1.6; 4.2) | |
Potential reduction of diagnostic delay among all patients (yr) median (range) (IQR) | 0 (0; 6.8) (0; 2) | 2 (0; 12.6) (0.6, 2.8) | 1.5 (0; 9.6) (0; 3) | 0 (0; 1.5) (0; 0) | 0 (0; 4.5) (0; 0) | 0 (0; 6.5) (0; 0) | 2.3 (0; 12.6) (1.5; 3.6) |
*over 1 year.
**over 1 year in children older than 2 years of age.
***over 2 years.
CI: confidence interval 95%.
IQR: interquartile range.
SDS: standard deviation score.