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. 2011 Jan 27;6(1):e16527. doi: 10.1371/journal.pone.0016527

Figure 3. Correlations between bispecific antibodies (BsAb) and various IgGs in RA patients.

Figure 3

For the 66 RA patients, BsAb, IgG anti-CCP, IgG RF, IgG4 anti-CCP, and IgG4 RF were determined by ELISA in duplicate. The mean optical densities at 450 nm with wavelength correction at 620 nm (OD450/620 nm) were obtained. The relationship of BsAb with IgG anti-CCP (A), IgG RF (B), IgG4 anti-CCP (C), and IgG4 RF (D) were assessed by Spearman's rank correlation coefficient. Two-sided p-values less than 0.05 were considered statistically significant.