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Case 1 serum prolactin concentration (IU/litre) and cross-sex hormone treatment protocol. During the first 18 months of treatment the serum prolactin rose to a maximum of 1.0 IU/litre, then normalised. After 14 years of treatment autonomous hyperprolactinaemia occurred. This was successfully treated with quinagolide 75 μg daily, after which the serum prolactin concentration returned to within reference levels.
