Table 1.

Proteinuria observed in sFLT1-induced preeclamptic mice

Lentiviral vector	n	Albumin/creatinine	P
LV-EGFP	12	5.27 ± 0.74	—
LV-hsFLT1	14	7.47 ± 0.61	0.03
LV-hsFLT1 (PD)	5	4.50 ± 0.38	0.52
LV-hsFLT1 + pravastatin	8	4.06 ± 0.38	0.23
LV-hsFLT1 + LV-mPGF	15	6.41 ± 0.61	0.24

Blastocysts were transduced with lentiviral vectors at 100 ng of p24/mL. Pravastatin was administered at 5 μg per body every day starting at E7.5. Urine was collected at E18.5 or 1 wk postdelivery (PD) and analyzed. Average ± SEM. Student's t test was performed against LV-EGFP treatment.