Table 1.

Localization of activated transferred T cells inside islets of Langerhans

	Mean % of infiltrated islets	SD	Median no. of T cells per infiltrated islets
3A9 into	0	0	0
No transfer
IP-HEL
5 min	4	0	1
1 h	6	0	2
2 h	3	0	1
8 h	7	4	2
12 h	19	8.9	2
24 h	55	19.8	11
48 h	95	10.7	48
BDC into
No transfer	0	0	0
NOD Rag1−/−
24 h	12	1.8	3
48 h	58	16.4	11
72 h	94	6.3	29

3A9 and BDC CD4 T cells were detected with their clonotype-specific antibody or anti-CD4.