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Proteins moving lipids moving proteins. A WALP23 (orange spheres), initially located in the Lo phase (green), gets incorporated into the Ld phase (red) through concerted peptide and lipid motion. (A) A peninsula of di-C18∶2PC lipids bridges the peptide to the core of the Ld domain. (B) The peptide gathers an island of di-C18∶2PC lipids (red) in its environment. (C and D) The di-C18∶2PC island merges with the Ld domain, and the peptide subsequently diffuses away from the domain boundary.
