Table 1.

Free energies, enthalpies, and entropies at 300 K of partitioning of single peptides between the Lo and Ld phases

	ΔGLo/Ld*	ΔHLo/Ld†	-TΔSLo/Ld†
WALP23	−63 ± 8	−594 ± 47	531 ± 48
WALP31	−58 ± 8	−276 ± 33	218 ± 34

All values are in kJ mol^-1.

^*ΔG_Lo/Ld was obtained from TI simulations.

^†ΔH_Lo/Ld was estimated from the system’s potential energy, and -TΔS_Lo/Ld = ΔG_Lo/Ld - ΔH_Lo/Ld. Standard errors are given (see SI Appendix). Note, the decomposition of the free energy into enthalpy and entropy, and thus the absolute values of ΔH_Lo/Ld and ΔS_Lo/Ld, should be interpreted at a qualitative level (see SI Appendix).