Table 3.

Comparative rate constants for the reaction of CO₂ and M-OH groups

Reactant	k2 or kcat/KM, M-1 s-1*	Ref.
[LnMIII-OH]z+	41–590	(18†–20)
[Zn(cyclen)(OH)]1+	3.3 × 103	(17)
OH-	7.9 × 103	(21)
Human carbonic anhydrase‡	1.1 × 105 to 1.6 × 108	(17)

^*Aqueous solution, pH ∼ 7–9 (where specified).

^†See additional data and references cited therein.

^‡k_cat/K_M.