Skip to main content
. 2011 Feb;22(2):285–295. doi: 10.1681/ASN.2010060647

Figure 1.

Figure 1.

Early mortality and renal failure in CfH-deficient MRL-lpr mice. (A) Early mortality in CfH−/− MRL-lpr mice. Shown are survival rates from the three groups of MRL-lpr mice over 24 weeks. (B) CfH−/− MRL-lpr mice had significantly higher albuminuria than littermate CfH+/− or CfH+/+ MRL-lpr mice at 12 weeks of age. Shown are individual urinary albumin/creatinine ratios (mg/mg) in all mice from each group at 8 and 12 weeks of age. (C) CfH−/− MRL-lpr mice, but not littermate CfH+/− or CfH+/+ MRL-lpr mice, developed renal failure at 12 weeks of age. Shown are individual BUN values in all mice from each group at 12 weeks of age. Horizontal bars depict the means of each group. *P = 0.044, **P = 0.012, and #P ≤ 0.001 versus CfH+/− and CfH+/+ MRL-lpr mice.