Table 3.
Features of cellular immunity in CfH−/− MRL-lpr mice
| Cells (origin) | Feature | 8 Weeks |
12 Weeks |
||
|---|---|---|---|---|---|
| CfH+/+ | CfH−/− | CfH+/+ | CfH−/− | ||
| Spleen weight/body weight (mg/g) | 4.4 ± 0.4 | 5.4 ± 0.6 | 6.3 ± 1.5 | 8.2 ± 1.3 | |
| CD4+ (spleen) | CD25+ | 16.0 ± 0.5 | 15.7 ± 0.6 | 13.2 ± 3.0 | 16.2 ± 2.2 |
| CD69+ | 29.8 ± 2.1 | 29.4 ± 2.1 | 33.3 ± 1.2 | 33.0 ± 1.7 | |
| CD62LlowCD44high | 45.5 ± 1.8 | 46.7 ± 3.4 | 63.5 ± 4.5 | 63.5 ± 1.3 | |
| CD4+ (renal lymph nodes) | CD25+ | 13.7 ± 1.5 | 12.3 ± 1.7 | 10.7 ± 1.2 | 9.9 ± 0.6 |
| CD69+ | 28.4 ± 1.7 | 26.3 ± 2.1 | 28.5 ± 1.6 | 29.6 ± 2.1 | |
| CD62LlowCD44high | 32.6 ± 1.2 | 34.4 ± 5.3 | 34.4 ± 1.9 | 32.8 ± 2.5 | |
Shown is the percentage of the individual cells within the total CD4+ population. Data are means ± SEM.