Table 1.
CTR |
S/CYC |
BTZ |
|||||||
---|---|---|---|---|---|---|---|---|---|
Before Treatment | 1 Week of Treatment | At Sacrifice | Before Treatment | 1 Week of Treatment | At Sacrifice | Before Treatment | 1 Week of Treatment | At Sacrifice | |
Erythrocytes × 1012 | 9.5 ± 0.5 | 7.1 ± 0.4b | 6.7 ± 1.1b | 10.4 ± 0.7 | 8.7 ± 0.8 | 8.4 ± 0.8 | 11.1 ± 0.3 | 10.3 ± 0.8a | 6.6 ± 1.0b |
Thrombocytes × 109 | 1120 ± 187 | 1109 ± 202 | 1460 ± 182 | 987 ± 137 | 1302 ± 87a | 893 ± 141 | 1102 ± 160 | 639 ± 162a | 1118 ± 314 |
Leukocytes × 109 | 8.3 ± 2.0 | 8.2 ± 0.7 | 8.1 ± 2.0 | 8.4 ± 1.7 | 7.8 ± 0.9 | 4.9 ± 0.8 | 8.7 ± 1.1 | 7.2 ± 1.2 | 7.7 ± 2.3 |
Lymphocytes × 109 | 5.6 ± 0.9 | 5.3 ± 0.5 | 4.7 ± 1.3 | 5.1 ± 0.7 | 5.1 ± 0.6 | 2.8 ± 0.4b | 5.9 ± 0.8 | 5.0 ± 0.7 | 4.9 ± 1.2 |
Granulocytes × 109 | 2.7 ± 0.8 | 2.1 ± 0.3 | 2.6 ± 0.8 | 2.4 ± 0.7 | 1.9 ± 0.3 | 2.1 ± 0.2 | 2.0 ± 0.3 | 1.7 ± 0.4 | 2.2 ± 1.0 |
Monocytes × 109 | 1.0 ± 0.3 | 0.8 ± 0.1 | 0.7 ± 0.2 | 0.9 ± 0.3 | 0.8 ± 0.1 | 0.6 ± 0.1 | 0.8 ± 0.1 | 0.5 ± 0.2 | 0.6 ± 0.2 |
The table shows the effect of S/CYC and BTZ in comparison to CTR.
aIndicates a significant difference compared to the control group at the indicated time point.
bIndicates a significant difference compared to the titer at randomization, P < 0.05.