Table 1.

Analysis of peripheral blood cell counts before, 1 week after start of treatment and at sacrifice

	CTR			S/CYC			BTZ
	Before Treatment	1 Week of Treatment	At Sacrifice	Before Treatment	1 Week of Treatment	At Sacrifice	Before Treatment	1 Week of Treatment	At Sacrifice
Erythrocytes × 1012	9.5 ± 0.5	7.1 ± 0.4b	6.7 ± 1.1b	10.4 ± 0.7	8.7 ± 0.8	8.4 ± 0.8	11.1 ± 0.3	10.3 ± 0.8a	6.6 ± 1.0b
Thrombocytes × 109	1120 ± 187	1109 ± 202	1460 ± 182	987 ± 137	1302 ± 87a	893 ± 141	1102 ± 160	639 ± 162a	1118 ± 314
Leukocytes × 109	8.3 ± 2.0	8.2 ± 0.7	8.1 ± 2.0	8.4 ± 1.7	7.8 ± 0.9	4.9 ± 0.8	8.7 ± 1.1	7.2 ± 1.2	7.7 ± 2.3
Lymphocytes × 109	5.6 ± 0.9	5.3 ± 0.5	4.7 ± 1.3	5.1 ± 0.7	5.1 ± 0.6	2.8 ± 0.4b	5.9 ± 0.8	5.0 ± 0.7	4.9 ± 1.2
Granulocytes × 109	2.7 ± 0.8	2.1 ± 0.3	2.6 ± 0.8	2.4 ± 0.7	1.9 ± 0.3	2.1 ± 0.2	2.0 ± 0.3	1.7 ± 0.4	2.2 ± 1.0
Monocytes × 109	1.0 ± 0.3	0.8 ± 0.1	0.7 ± 0.2	0.9 ± 0.3	0.8 ± 0.1	0.6 ± 0.1	0.8 ± 0.1	0.5 ± 0.2	0.6 ± 0.2

The table shows the effect of S/CYC and BTZ in comparison to CTR.

^aIndicates a significant difference compared to the control group at the indicated time point.

^bIndicates a significant difference compared to the titer at randomization, P < 0.05.