Table 3.

Differences in body composition Z-scores between CKD groups and healthy controls

	Adjusted Difference in Z-Score versus Controls
	Mean Difference [95% CI]
	CKD 2 to 3	CKD 4 to 5	Dialysis
DXA lean mass and pQCT calf muscle CSA
whole body LM-for-height	0.36 [0.12, 0.60], P = 0.003	0.24 [−0.04, 0.52], P = 0.1	−0.32 [−0.65, −0.002], P = 0.05
trunk LM-for-sitting height	0.18 [−0.06, 0.42], P = 0.15	0.50 [0.22, 0.79], P = 0.001	0.39 [0.06, 0.71], P = 0.02
leg LM-for-leg length	0.02 [−0.20, 0.24], P = 0.8	−0.41 [−0.66, −0.15], P = 0.002	−1.03 [−1.32, −0.74], P < 0.0001
calf muscle CSA-for-tibia length	0.007 [−0.25, 0.26], P = 0.9	−0.10 [−0.38, 0.18], P = 0.5	−0.74 [−1.06, −0.42], P < 0.0001
DXA fat mass and pQCT calf fat CSA
whole body FM-for-height	0.12 [−0.16, 0.40], P = 0.4	0.41 [0.08, 0.73], P = 0.01	0.04 [−0.33, 0.42], P = 0.8
trunk FM-for-sitting height	0.44 [0.17, 0.72], P = 0.002	0.73 [0.41, 1.06], P < 0.0001	0.43 [0.05, 0.80], P = 0.03
leg FM-for-leg length	−0.07 [−0.35, 0.21], P = 0.6	0.11 [−0.21, 0.44], P = 0.5	−0.32 [−0.69, 0.06], P = 0.1
calf Fat CSA-for-tibia length	−0.06 [−0.37, 0.24], P = 0.7	0.11 [−0.23, 0.45], P = 0.5	−0.37 [−0.75, 0.008], P = 0.06

Differences are adjusted for age, sex, pubertal status, study site (CHOP versus CCHMC), and height (height for whole body, sitting height for trunk, and leg length for leg).