Table 2.

Melting temperatures relative to folding temperatures

Potential	Length	Tf	Tm	Tm/Tf
Be	50	0.3	0.2	0.66
Be	60	0.34	0.19	0.55
Be	70	0.3	0.27	0.89
Be	80	0.25	0.25	1.02
〈Be〉	—	0.3	0.23	0.76
P0	50	0.18	0.15	0.86
P0	60	0.2	0.13	0.63
P0	70	0.24	0.21	0.87
P0	80	0.19	0.19	1.0
〈P0〉	—	0.2	0.17	0.84
P1	50	0.41	0.12	0.29
P1	60	0.39	0.09	0.22
P1	70	0.4	0.12	0.31
P1	80	0.36	0.08	0.22
〈P1〉	—	0.39	0.1	0.26
P2	50	0.4	0.08	0.2
P2	60	0.46	0.1	0.22
P2	70	0.4	0.08	0.2
P2	80	0.51	0.08	0.16
〈P2〉	—	0.44	0.09	0.19

The structure and sequences of the designed proteins are given in the Supporting Material. Average T_m/T_f values over the four structures designed with the same potential are indicated in bold.