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. Author manuscript; available in PMC: 2011 Jul 6.
Published in final edited form as: N Engl J Med. 2010 Dec 9;364(1):33–42. doi: 10.1056/NEJMoa1012928

Figure 2. Reconstructing Phylogenetic Relationships among V. cholerae Strains.

Figure 2

Panel A shows the phylogenetic relationships among pandemic V. cholerae strains on the basis of single- nucleotide variations identified among all strains for which a set of 1588 orthologous genes has been completely sequenced.10 The magnified inset represents strains in the seventh pandemic, including H1, H2, M4, C6, and N5. Panel B shows the phylogenetic relationships among a broad set of seventh-pandemic V. cholerae strains.19 The phylogenetic tree is rooted with three pre-seventh-pandemic strains.