Table 2.
Case 1 | Case 2 | Case 3 | Case 4 | |
---|---|---|---|---|
Age at XDR-TB diagnosis, years* | 7.5 | 7 | 7.5 | 6 |
Sex | Male | Male | Female | Female |
Reason for initial admission | Kwashiorkor and cough | Kwashiorkor, cough and diarrhea | Cough and fever | Lymphadenopathy |
TB history prior to admission (age at prior TB diagnosis, years) | Active PTB (5.5) | No | No | LTBI (3), scrofula (5) |
Duration of drug-susceptible TB treatment prior to XDR-TB diagnosis, months* | 3 | 6 | 6 | Data unavailable |
Duration as in-patient prior to XDR-TB diagnosis, months* | 17 | 8.5 | 7.5 | 5 |
CD4 count at time of HAART initiation, cells/mm3 (% lymphocytes) | 420 (13) | 177 (9) | Data unavailable | 406 (20) |
Time on HAART prior to XDR-TB treatment initiation, months | 16 | 0 | 9 | 6 |
Diagnosis is measured at the time the diagnostic sputum sample was sent.
XDR-TB = extensively drug-resistant tuberculosis; TB = tuberculosis; PTB = pulmonary TB; LTBI = latent TB infection; HAART = highly active antiretroviral therapy.