Blocking CRF receptors attenuates ethanol-mediated melanosome dispersal. A–D, Images of 5 dpf larvae with brain injection of DMSO control (A), CRF receptor-1 antagonist antalarmin (B), CRF receptor-2 antagonist K41498 (C) or both (D) and exposed to ethanol for 20 min. E, Quantification, ***p < 0.001, n = 12, one-way ANOVA.