Table 2.

Mucin-interacting partners and their interaction site/structure present in corresponding mucins

Mucin	Binding partner	Interaction site of specific mucins	Reference
MUC1a	β-catenin	SAGNGGSSL (SRM; serine rich motif) present in the CT	[47]
	HSP90	SAGNGGSSL (SRM; serine rich motif) present in the CT	[25]
	HSP70	CT (amino acids 46-72)	[45]
	FGFR3	CT (amino acids 46-72)	[25]
	γ-catenin	SAGNGGSSL (SRM; serine rich motif) present in the CT	[64]
	ER α	CT (amino acids 9-46)	[54]
	GRB2	pYTNP motif in the CT	[42]
	p53	CT (amino acids 9-46)	[53]
	IKKβ	CT (amino acids 1-45)	[44]
	IKKγ	CT (amino acids 46-72) specifically within the SAGNGGSSLS motif (SRM)	[44]
	galectin-3	TF-antigen	[16]
MUC17	PDZK1	TTSF motif present in the CT	[56]
MUC16	moesin	RRRKK, the polybasic sequence present in the CT	[55]
	galectin-3	O-glycans	[14]
	galectin-1	O-glycans	[13]
MUC20	Met	CT (amino acids 451-503)	[22]
MUC5B	histatin1 statherin and histatin 3 and 5	Cysl and Cys2 (in Tandem repeat region) and Cys8a (in C-terminus) Cys8a (in C-terminus)	[7]
MUC7	α-amylase, PRP2, PRP3, PRP4, statherin, histatin 1	N-terminal 144 residues of MUC7	[9]

^aFor the individual kinases that interact with the MUC1 CT, the phosphorylation site is considered to be the site of interaction.