FIGURE 2.
Characterization of SDS resistance of remodeled Aβ soluble oligomers. Aβ soluble oligomers (25 μm; formed after 1–2 days without agitation) were dosed with (A) myricetin and NDGA, (B) benzothiazole and riluzole, (C) methylene blue, and (D) tannic acid and piceid, and analyzed using SDS-PAGE. The Aβ conformational controls are freshly disaggregated Aβ (soluble low molecular weight (LMW)), fibrils, soluble oligomers remodeled by resveratrol (20 μm, 4 h), and soluble oligomers.