TABLE 2.
Inhibition of PvGGPPS by representative N-BPs (n > 5)
Average values ± S.D. were obtained from multiple repetitions (n > 5) of the 14C radioactivity assay described in Ref. 20.
N-BP | IC50 | Kiapp | Ki |
---|---|---|---|
nm | nm | nm | |
RIS | 47.5 ± 4.4 | 29.7 ± 4.0 | 12.4 ± 1.7 |
ZOL | 43.3 ± 3.3 | 25.8 ± 2.9 | 10.7 ± 1.2 |
IBAN | 61.9 ± 4.1 | 38.3 ± 4.5 | 16.0 ± 1.9 |