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. 2010 Nov 17;286(5):3315–3322. doi: 10.1074/jbc.M109.027235

TABLE 2.

Inhibition of PvGGPPS by representative N-BPs (n > 5)

Average values ± S.D. were obtained from multiple repetitions (n > 5) of the 14C radioactivity assay described in Ref. 20.

N-BP IC50 Kiapp Ki
nm nm nm
RIS 47.5 ± 4.4 29.7 ± 4.0 12.4 ± 1.7
ZOL 43.3 ± 3.3 25.8 ± 2.9 10.7 ± 1.2
IBAN 61.9 ± 4.1 38.3 ± 4.5 16.0 ± 1.9